BCH 6207
Role of Membranes in Signal Transduction
and Metabolic Control
FALL 2006
M, W, F - Period 2 (
In this 5-week course, we will examine the role of membranes in signal transduction and metabolic control at a more advanced level than the introductory courses, with a focus on regulation. Thus, students are expected to have performed well in an introductory course in Biochemistry. Courses such as BCH 4204, CHM 4207, CHM 3218, BCH 3025 or GMS 6001 are considered appropriate introductory courses.
The text, "Biochemistry" by Voet and Voet (2004, 3rd edition), will serve as a general reference. For those interested in human meetabolism, "Metabolic Regulation: A Human Perspective" by K.N.Frayn is optional. Outside reading in primary journals, reviews and special monographs will be assigned when appropriate. Extensive use will be made of handouts throughout the course.
Each lecture title represents the general area to be covered. Brief reviews of the relevant pathways will be given but the lectures will focus on selected topics related to enzyme action; allosteric regulation and its relevance to enzyme mechanism and metabolic function; and/or genetic regulation of an enzyme or group of enzymes in a related pathway.
EXAMINATION SCHEDULE
There will be one - three hour examination. This will be composed of essay, short answer, and other question types.
Thursday, September 28th,
CORE INSTRUCTORS email
Dr. Susan Frost, Professor (Course Coordinator) R3-216A, 392-3207 sfrost@ufl.edu
Dr. Tom O'Brien, Professor R2-295, 392-6878 tobrien@ufl.edu
GUEST LECTURERS
Dr. Bruce Stevens, Professor, Physiology 392-4480, D-529 stevens@phys.med.ufl.edu
Dr. Michael Kilberg, Professor, BMB 392-2711,
R3-116B mkilberg@ufl.edu
click here to see lecture topics