1) DNA Methylation in Mammalian Cells.

Relevant publications:

1. Robertson, KD and Wolffe, AP. DNA methylation in health and disease. Nature Rev.Genet. 1: 11-19, 2000.  (click to view as PDF)

2. Robertson, KD. DNA methylation, methyltransferases, and cancer. Oncogene 20: 3139-3155, 2001.  (click to view as PDF)

3. Robertson, KD. DNA methylation and chromatin structure: Unraveling the tangled web. Oncogene 21: 5361-5379, 2002.  (click to view as PDF)

4. Geiman, TM and Robertson, KD. Chromatin remodeling, histone modifications, and DNA methylation — how does it all fit together? J. Cell. Biochem. 87: 117-125, 2002.

5. Yokochi, T and Robertson, KD. Preferential methylation of unmethylated DNA by mammalian de novo DNA methyltransferase Dnmt3a. J. Biol. Chem. 277: 11735-11745, 2002.  (click to view as PDF)

6. Tao, Q, Huang, H, Geiman, TM, Lim, CY, Fu, L, Qiu, G-H, Robertson, KD. Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum. Mol. Genet. 11(18): 2091-2102, 2002.  (click to view as PDF)

7. Tao, Q and Robertson, KD. Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection. Clin. Immunol. 103: 53-63, 2003.

8. Robertson, KD. DNA methylation and human disease. Nature Rev. Genet. 6: 597-610, 2005.  (click to view as PDF)

9. Brown, KD, Robertson, KD. DNMT1 knockout delivers a strong blow to genome stability and cell viability. Nature Genet. 39(3): 289-290, 2007.  (click to view as PDF)

10. Palii, SS, Robertson, KD. Epigenetic control of tumor suppression. Crit. Rev. Euk. Gene Exp. 17(4): 295-316, 2007.  (click to view as PDF)

11. Van Emburgh, BO, Robertson, KD. DNA methyltransferases and methyl-CpG binding proteins as multi-functional regulators of chromatin structure and development in mammalian cells, In Epigenetics, pp. 23-62 (J. Tost, ed.). Caister Academic Press, 2008.