CoursesGraduate courses appear below. Click here for undergraduate courses.Molecular Biology CoursesMetabolism and Cell Biology CoursesStructural Biology/Advanced Physical Biochemistry CoursesJournal Clubs and SeminarsLaboratory and Other CoursesMolecular Biology CoursesBCH 5413 Mammalian Molecular Biology and Genetics3 credits, Spring semester only The course will emphasize biochemical and genetic approaches to understanding vertebrate and particularly mammalian molecular biology, moving from the basic processes of replication, transcription and protein synthesis to signal transduction, the cell cycle, cancer, genomics and developmental genetics. Course Coordinator: Philip J.
Laipis, Ph.D.
BCH
6415 Advanced Molecular and Cell Biology
An advanced course in the molecular biology of pro- and eukaryotic organisms, with an emphasis on understanding the experimental approaches which have led to recent developments in the field. Topics include chromosome structure and organization, advances in recombinant DNA technology, DNA replication, RNA transcription and protein synthesis, and selected aspects of the molecular regulation of gene expression. Students who have performed well in one of the following courses, BCH 4024, CHM 4207, or MCB 4303, should be adequately prepared for this course. PCB 3063 or a similar course in genetics will be helpful. Students lacking these prerequisites can be admitted with consent of instructor. For more detailed information, link to BCH 6415. Course Coordinator: Philip J.
Laipis, Ph.D.
BCH 7410 Advanced Gene Regulation
This course will served as a literature-based assessment of the most recent advances in factors governing eucaryotic gene regulation. This course will consist of a series of faculty lectures, group discussions and student presentations at the level of original research papers. Course Coordinator: Brian D.
Cain, Ph.D.
Metabolism and Cell Biology CoursesBCH 6206 Advanced Metabolism3 credits, Fall semester only The reactions of intermediary metabolism with emphasis upon their integration, mechanism. and control. One of the three core departmental courses. Course Coordinator: Susan C.
Frost, Ph.D.
BCH
6207 Advanced Metabolism: Role of Membranes in Signal Transduction
and Metabolic Control
Fundamentals of membrane biochemistry. The course will include discussions of membrane structure, nutrient and ion transport, protein targeting, signal transduction. Students will learn experimental methods and techniques used to gather and analyze data related to membrane biochemistry and its regulation. Course Coordinator: Susan C.
Frost, Ph.D.
BCH
6208 Advanced Metabolism: Regulation of Key Reactions in Carbohydrate
and
Lectures will emphasize key reactions in the metabolic pathways of carbohydrate and lipid metabolism with special attention to the exploration of the experimental basis for our current understanding of these processes. Understanding of the interactions between major metabolic pathways and control of these pathways under different physiological conditions are central themes of the course. Course Coordinator: Susan C.
Frost, Ph.D.
BCH
6209 Advanced Metabolism: Regulation of Key Reactions in Amino Acid
and Nucleotide Metabolism
Lectures will emphasize key reactions in the metabolic pathways of amino acid and nucleotide metabolism with special attention to understanding interactions between major metabolic pathways and control of these pathways under different physiological conditions. Special emphasis will be placed on the structural basis of enzyme function and regulation. Course Coordinator: Charles M.
Allen, Ph.D.
BCH 6296 Nutrient Control of Gene
Expression: Application to Metabolic Diseases
Structural Biology/Advanced Physical Biochemistry CoursesBCH 6740 Structural Biology/Advanced Physical Biochemistry3 credits, Spring semester only Physical chemistry of biological molecules and the techniques for their study. Constitutes one of the three core departmental courses. Course Coordinator: Daniel L.
Purich, Ph.D.
BCH
6746 Structural Biology/Advanced Physical Biochemistry: Macromolecular
Structure, Dynamics, and Interactions
This module will provide instruction in experimental approaches to biological macromolecular structure determination, with emphasis on current understanding of protein-protein, protein-nucleic acid structure motifs, dynamics and aspects of protein folding. Course Coordinator: Thomas H.
Mareci, Ph.D.
BCH
6747 Structural Biology/Advanced Physical Biochemistry: Spectroscopy and
The first half of the class will focus on the application of spectroscopic techniques (circular dichroism, fluorescence, nuclear magnetic resonance) to determine the structure of biological macromolecules. The second half will cover hydrodynamic approaches including light scattering, molecular diffusion, viscosity and ultracentrifugation. Course Coordinator: Robert J.
Cohen, Ph.D.
BCH
7515 Structural Biology/Advanced Physical Biochemistry: Kinetics and Thermodynamics
This module will provide the student with the fundamentals of chemical kinetics and thermodynamic analysis of equilibria. The emphasis will be the application of this knowledge to our understanding of basic enzyme kinetics, pulse-chase kinetics, protein polymerization, DNA dynamics, protein-nucleic acid interactions and cooperative ligand binding. Course Coordinator: Daniel L.
Purich, Ph.D.
Journal Clubs and SeminarsBCH 6876 Recent Advances in Membrane Biology Journal Club1 credit, Fall and Spring semesters (not offered 1999-2000) Literature of membrane biology, presented
by students and faculty, discussed in depth. Emphasis is on current developments,
data interpretation and critical analysis. Classes are held informally
in small groups.
BCH 6877 Recent Advances in Structural
Biology Journal Club
Literature on structural biology, presented by students and faculty, discussed in depth. Emphasis is on current developments, data interpretation and critical analysis. Classes are held informally in small groups. Course Coordinator: A.S. Edison,
Ph.D.
BCH 6878 Recent Advances in Cytoskeletal
Processes Journal Club
Literature on cytoskeletal processes, presented by students and Biochemical research in which the student
refines research techniques in physical biochemistry intermediary metabolism,
molecular biology and cell biology under the supervision of a staff member.
BCH 6910 Supervised Research
Open only to departmental graduate students.
B.S. in Biochemistry and Molecular Biologyfrom the College of Liberal Arts and Sciences' Interdisciplinary Studies (IDS) ProgramLECTURE BASED COURSESBCH 4024: Introduction to Biochemistry and Molecular Biology4 credits offered Fall, Spring, and Summer C semesters RESEARCH BASED COURSESBCH 4905: Biochemistry Senior Research1-7 credits offered every semester (limited to IDS students only) BMS 4905: Medical Sciences Senior
Research
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