BCH
5413 Mammalian Molecular Biology and Genetics
3 credits, FALL
The course emphasizes biochemical and genetic approaches to understanding vertebrate and particularly mammalian molecular biology, moving from the basic processes of replication, transcription and protein synthesis to signal transduction, the cell cycle, cancer, genomics and developmental genetics. The course is intended for advanced undergraduate students or beginning graduate students in the life sciences. Students who have performed well in one of the following courses, BCH 4024, CHM 4207, or MCB 4303, should be adequately prepared for this course. PCB 3063 or a similar course in genetics will be helpful. Students lacking these prerequisites can be admitted with consent of instructor. Students interested in research careers in molecular biology should consider enrolling in BCH 6415 after taking BCH 5413.
BCH
6415 Advanced Molecular and Cell Biology
3 credits, Spring
An advanced course in the molecular biology of pro- and eukaryotic organisms, with an emphasis on understanding the experimental approaches which have led to recent developments in the field. Topics include chromosome structure and organization, advances in recombinant DNA technology, DNA replication, RNA transcription and protein synthesis, and selected aspects of the molecular regulation of gene expression. Students who have performed well in BCH 5413 or GMS 6001 should be adequately prepared for this course. Students lacking these prerequisites can be admitted with consent of instructor.
Other Teaching and Related Course Materials
Lecture notes for VEM 5131, Introduction to Transgenic Animals and
Gene
Therapy Methods. Notes in Adobe Acrobat format.
Genetic
Engineering: Transgenics and Gene Therapy 2006
Gene Therapy: Lecture Notes extra (PKU)
Lecture notes for GMS 6004: Cloning, expression, mutagenesis, and kinetic analysis of carbonic anhydrase isozymes II and III.
The
Structure and Molecular Biology of the Carbonic Anhydrases
BioMarin