University of Florida Department of Physiology and Functional Genomics


Bruce R. Stevens, Ph.D.
Professor
Phone: (352) 392-4480
Fax: (352) 846-0270
Office:

CG-020C, Health Science Center

E-mail: stevensb@ufl.edu
 

Research

Research in my laboratory centers on the cellular physiology, molecular biology, and regulation of organic solute transport across plasma membranes. Current research projects concern cytokine and peptide growth factor regulation of membrane L-arginine transporter isoforms in lymphocytes, cultured brain glial and neuronal cells, and cultured intestinal adenocarcinoma cells. Other projects concern the regulation of transporters and membrane-bound enzymes by specific nutrients. Using radiation inactivation by a 13-MeV linear accelerator, we are collaborating in investigating the molecular arrangement of membrane-bound transporter polypeptides and putative regulatory subunits. The cloning of specific transporters and the mechanism by which the polypeptides behave in membranes is being studied using electrophysiological techniques in oocytes injected with cRNA. An additional project in collaboration with NASA concerns myosin isoforms and the intermediary metabolism of amino acids in exercising skeletal muscle.

Publications

Patents

University Appointments




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