Home > Pain Research Investigators > Roland Staud, M.D.

Roland Staud, M.D., F.A.C.P, F.A.C.R.

Professor of Medicine

M.D. 'Summa Cum Laude'
Fellowship in Rheumatology at New York University.
Faculty member at the University of Florida since 1991.


Clinical Interests:
Chronic pain, myofascial pain, osteoarthritis, rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia, dermatomyositis/polymyositis, systemic sclerosis.


Research Interests:
Psycho-physical abnormalties in patients with chronic Musculoskeletal pain
Neural Imaging of Pain
The effects of exercise on chronic musculoskeletal pain
Delayed-onset muscle hypersensitivity (DOMS)

Research supported by the National Institute of Health (NIH)

Publications available online: R. Staud

  1. Effects of the NMDA Receptor Antagonist Dextromethorphan on Thermal and Mechanical Windup in Patients with Fibromyalgia and Normal Controls.
    Staud, R., Vierck, C.J., Robinson, M.E., Price, D.D.
    J.Pain 6:323-332 (2005)
  2. Sex-Related Psychological Predictors of Baseline Pain Perception and Analgesic Responses to Pentazocine.
    Fillingim, R.B, Hastie, B.A., Ness, T.J., Glover, T.J., Campbell, C.M., and Staud, R.
    Biol.Psych. 69(1):97-112 (2005)
  3. The A118G Single Nucleotide Polymorphism of the µ-Opioid Receptor Gene (OPRM1) is Associated with Pressure Pain Sensitivity in Humans.
    Fillingim, R. B., Kaplan, L., Staud, R., Ness, T.J., Glover, T.L., Campbell, C.M., Mogil, J.S., and Wallace, M.R
    J.Pain 6:159-167 (2005)
  4. Morphine and Experimental Pain: Sex Differences in Side Effects and Cardiovascular Responses but not Analgesia.
    Fillingim, R.B. Ness, T.J. Glover, T.L. Campbell, C.M. Price, D.D., Staud R.
    J.Pain 6:116-124 (2005)
  5. Abnormal Pain Processing in Patients with Fibromyalgia Syndrome.
    Staud, R.
    J.Chron.Fatigue Syndrome 12:71-77 (2004)
  6. Spatial Summation of Heat Pain within and across Dermatomes in Fibromyalgia Patients and Pain-Free Subjects.
    Staud, R., Vierck, C.J., Robinson, M.E., Price, D.D.
    Pain 111(3):342-350 (2004)
  7. Maintenance of Windup of Second Pain Requires Less Frequent Stimuli in Fibromyalgia Patients Compared to Normal Controls.
    Staud, R., Price D.D., Robinson, M.E., Mauderli, A.P., Vierck C.J.
    Pain 110(3):689-696 (2004)
  8. Body Pain Area and Pain Related Negative Affect Predict Clinical Pain Intensity in Patients with Fibromyalgia Syndrome
    Staud, R., Price, D.D., Robinson, M.E., Cannon, R.C., Vierck, C.J.
    J.Pain 5:338-343 (2004)
  9. Experimental Pain Models Reveal no Sex Differences in Pentazocine Analgesia.
    Fillingim, R.B., Ness, T.J., Glover, T.L., Campbell, C.M., Price, D.D., Staud R.
    Anesthesiology 100:1263-1270 (2004)
  10. Trial Report: Rheumatic Manifestations of Other Diseases.
    Staud, R
    Curr.Rheum.Report 6:259-260 (2004)
  11. Fibromyalgia Pain: Do We Know the Source?
    Staud, R.
    Curr.Opinion Rheum. 16:157-164 (2004)
  12. Central Sensitization Predicts Clinical Pain in Fibromyalgia Syndrome.
    Staud, R.
    Curr.Rheum.Report 6:281-286 (2004)
  13. Fibromyalgia: What are the long term prospects?
    Staud R.
    J.Musculoskel.Med. 21:290 (2004)
  14. Survival in Academy Award Winning Actors and Actresses.
    Staud R.
    Ann.Int.Med. 138:77 (2003)
  15. Diffuse Noxious Inhibitory Controls (DNIC) Attenuate Temporal Summation of Second Pain in Normal Males but not in Normal Females or Fibromyalgia Patients.
    Staud R., Robinson M.E., Vierck C.J., Jr., Price D.D.
    Pain 101:167-174 (2003)
  16. Temporal Summation of Pain from Mechanical Stimulation of Muscle Tissue in Normal Controls and Patients with Fibromyalgia Syndrome.
    Staud R., Cannon R.C., Mauderli A.P., Robinson M.E., Price D.D., and Vierck C.J.
    Pain 102:87-95 (2003)
  17. The Melanocortin-1 Receptor Gene Mediates Female-Specific Mechanisms of Analgesia in Mice and Humans.
    Mogil J.S., Wilson S.G., Chesler E.J., Rankin A.L, Nemmani K.V.S., Lariviere W.R, Groce M.K, Wallace M.R., Kaplan L., Staud R.,. Ness T.J, Glover T.L., Stankova M., Mayorov A., Hruby V.J., Grisel J.E., and Fillingim R.B.
    PNAS 100:4867-72 (2003)
  18. Ratings of Experimental Pain and Pain-Related Negative Affect Predict Clinical Pain in Patients with Fibromyalgia Syndrome.
    Staud, R. Robinson, M.E., Vierck, C.J. Cannon, R.C., Mauderli, A.P., Price, D.D.
    Pain 105:215-222 (2003)
  19. Staud R.. Somatization does not Fit All Fibromyalgia Patients.
    Arthritis Rheum. 46:564-565 (2002)
  20. Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients.
    Price, D.D., Staud, R., Robinson, M.E., Mauderli, A.P., Cannon, R.L., Vierck C.
    J. Pain 99:49-59 (2002)
  21. Peripheral and Central Sensitization in Fibromyalgia: Pathogenetic Role.
    Staud, R., Smitherman, M.L.
    Curr. Pain Headache Res. 6:259-266 (2002)
  22. Somatization Does not Fit All Fibromyalgia Patients.
    Staud R.
    Arthritis Rheum. 46:564-565 (2002)
  23. New Insights into the pathogenesis of fibromyalgia syndrome.
    Staud R., Domingo M.
    Med.Asp.Human Sex. 1:51-57 (2001)
  24. The Effect of Exercise on Temporal summation of Second Pain (Wind-up) in Patients with Fibromyalgia Syndrome.
    Vierck, C.J. Staud, R., Price, D.D., Cannon R.L., Mauderli, A., Martin, A.D.
    J.Pain 2:334-345 (2001)
  25. Evidence of abnormal pain processing in fibromyalgia syndrome.
    Staud, R., Domingo M.. Pain Med. 2:208-215 (2001)
  26. New Insights into the pathogenesis of fibromyalgia syndrome.
    Staud R. and M. Domingo.
    Med.Asp.Human Sex. 1:51-57 (2001)
  27. Evidence for abnormal pain processing in fibromyalgia syndrome.
    Staud, R. and M. Domingo.
    Pain Medicine 2:1-8 (2001)
  28. Influenza A Associated Bronchiolitis Obliterans Organizing Pneumonia (BOOP) Mimicking Wegener's Granulomatosis.
    Staud, R. and L.G. Ramos.
    Rheumatol.Int. 20:125-128 (2001)
  29. Abnormal sensitization and temporal summation of second pain (wind-up) in patients with fibromyalgia syndrome.
    Staud, R., Vierck, C.J., Cannon, R.L., Mauderli, A.P., Price, D.D.
    Pain 91:165-175 (2001)
  30. Amphipathic variable region heavy chain peptides derived from monoclonal human Wegener's anti-PR3 antibodies stimulate lymphocytes from patients with Wegener's granulomatosis and microscopic polyangiitis.
    Peen E., Malone, C., Myers, C., Williams Jr., R.C., Peck, A.B., Csernok, E., Gross, W.L., Staud, R.
    Clin.Exp.Immunol 125:323-331 (2001)
  31. Comparing the COX-2 Inhibitors with traditional NSAIDs.
    Staud, R.
    Emergency Med. 32(11):13-19 (2000)
  32. A Place for NSAIDs
    Staud, R.
    Int.Med.News 32(19):8 (1999)
  33. Osteoporosis: When to measure bone mineral density?
    Staud, R.
    J.Musculoskel.Med 15(9):25-32(1998)
  34. Abnormal temporal summation of second pain (wind-up) in patients with the fibromyalgia syndrome.
    Staud, R., C.J. Vierck, A. Mauderli, R. Cannon.
  35. Arthritis Rheum 41(9): S353 (1998)
    Hepatic Artery Rupture And Renal Infarction: Two Complications of Fibromuscular Dysplasia that mimic Vasculitis.
    H. J. Jones, R. Staud, and R. C. Williams, Jr.
    J.Rheumatol 25:215-218 (1998)
  36. Wegener's granulomatosis in a Patient receiving Propylthiouracil for Graves' disease
    M. Pillinger and R. Staud
    Semin.Arthritis Rheum 28:124-129 (1998)
  37. Antineutrophilic Cytoplasmic Antibodies (cANCA) Reacting with Peptides of Proteinase-3.
    R.Staud and B. Blood
    Arthritis Rheum. 39(9):S218 (1996)
  38. "Vasculitis Look-Alike" Clinical Syndromes
    R. Staud, B.Yancey and R.C. Williams
    J.Clin.Rheum. 2:203-208 (1996)
  39. Association of Parvovirus B19 infection with Giant Cell Arteritis.
    R. Staud and L. Corman
    Clin.Inf.Dis. 22:1123 (1996)
  40. Brain Abscess Mimicking Giant Cell (Temporal) Arteritis
    Staud R. and R.C. Williams,Jr.
    Arthritis Rheum. 38 (11):1710-1712 (1995)
  41. Epitopes of Proteinase 3 are Recognized by T Cells of Patients with Wegener's Granulomatosis.
    R. Staud and G. Fry
    Arthritis Rheum. 38(9):S375 (1995)
  42. Brain Abscess Mimicking Temporal Arteritis.
    R. Staud and R.C. Williams,Jr.
    Arthritis Rheum. 38 (11):1710-1712 (1995)
  43. Activation-Dependent Carboxyl Methylation of Neutrophil G-Protein g Subunit.
    M.R. Philips, R.Staud, M.H.Pillinger, J.B.Stock, A.Feoktistov, C. Volker, J.B.Stock, and G. Weissmann.
    Proc.Natl.Acad.Sci.USA. 92 (6): 2283-2287 (1995)
  44. Minocycline was Effective for Mild to Moderate Rheumatoid Arthritis.
    R. Staud
    ACP J.Club 122 (3):69 (1995)
  45. Antineutrophilic Cytoplasmic Antibodies (ANCA) and Vasculitis.
    R. Staud and R.C. Williams Jr.
    Comprehensive Therapy. 20: 623-627 (1994)
  46. Nurse Practitioners were More Effective than Physicians in a Rheumatology Clinic.
    R. Staud.
    ACP J.Club 121 (2): 45 (1994)
  47. Epitopes on Proteinase-3 Recognized by Antibodies from Patients with Wegener's Granulomatosis.
    R.C. Williams Jr., R. Staud, C.C. Malone, J. Payabyab, L. Byres, and D. Underwood.
    J.Immunol. 152: 4722-4737 (1994)
  48. Carboxyl Methylation of Ras-Related Proteins during Signal Transduction in Neutrophils.
    M.R. Philips, Pillinger M.H.,Staud R.,Volker C., Rosenfeld M.G., Weissmann G. and J.B. Stock.
    Science. 259, 977-980 (1993)